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Mucosal Progranulin expression is induced by H. pylori, but independent of Secretory Leukocyte Protease Inhibitor (SLPI) expression

BACKGROUND: Mucosal levels of Secretory Leukocyte Protease Inhibitor (SLPI) are specifically reduced in relation to H. pylori-induced gastritis. Progranulin is an epithelial growth factor that is proteolytically degraded into fragments by elastase (the main target of SLPI). Considering the role of S...

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Detalhes bibliográficos
Main Authors: Wex, Thomas, Kuester, Doerthe, Schönberg, Cornelius, Schindele, Daniel, Treiber, Gerhard, Malfertheiner, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115905/
https://ncbi.nlm.nih.gov/pubmed/21612671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-11-63
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