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The cortical protein Lte1 promotes mitotic exit by inhibiting the spindle position checkpoint kinase Kin4
The spindle position checkpoint (SPOC) is an essential surveillance mechanism that allows mitotic exit only when the spindle is correctly oriented along the cell axis. Key SPOC components are the kinase Kin4 and the Bub2–Bfa1 GAP complex that inhibit the mitotic exit–promoting GTPase Tem1. During an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115795/ https://ncbi.nlm.nih.gov/pubmed/21670215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201101056 |
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