WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane

Tail-anchored (TA) proteins are post-translationally targeted to and inserted into the endoplasmic reticulum (ER) membrane through their single C-terminal transmembrane domain. Membrane insertion of TA proteins in mammalian cells is mediated by the ATPase TRC40/Asna1 (Get3 in yeast) and a receptor i...

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Bibliographic Details
Main Authors: Vilardi, Fabio, Lorenz, Holger, Dobberstein, Bernhard
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115773/
https://ncbi.nlm.nih.gov/pubmed/21444755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.084277
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