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Guiding Neuronal Growth Cones by Ca(2+) Signals: During axon pathfinding in the developing nervous system, spatiotemporal patterns of Ca(2+) signals can govern growth cone extension and steering—by symmetric versus asymmetric regulation of cytoskeletal and membrane dynamics

Pathfinding by growing axons in the developing or regenerating nervous system may be guided by gradients of molecular guidance cues. The neuronal growth cone, at the ends of axons, uses surface receptors to sense these cues and transduce guidance information to cellular machinery that mediates growt...

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Detalhes bibliográficos
Main Authors: Henley, John, Poo, Mu-ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115711/
https://ncbi.nlm.nih.gov/pubmed/15183189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2004.04.006
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