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Individual Polychlorinated Biphenyl (PCB) Congeners Produce Tissue- and Gene-Specific Effects on Thyroid Hormone Signaling during Development

Polychlorinated biphenyls (PCB) are industrial chemicals linked to developmental deficits that may be caused in part by disrupting thyroid hormone (TH) action by either reducing serum TH or interacting directly with the TH receptor (TR). Individual PCB congeners can activate the TR in vitro when the...

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Detalhes bibliográficos
Main Authors: Giera, Stefanie, Bansal, Ruby, Ortiz-Toro, Theresa M., Taub, Daniel G., Zoeller, R. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115602/
https://ncbi.nlm.nih.gov/pubmed/21540284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1490
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