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Individual Polychlorinated Biphenyl (PCB) Congeners Produce Tissue- and Gene-Specific Effects on Thyroid Hormone Signaling during Development

Polychlorinated biphenyls (PCB) are industrial chemicals linked to developmental deficits that may be caused in part by disrupting thyroid hormone (TH) action by either reducing serum TH or interacting directly with the TH receptor (TR). Individual PCB congeners can activate the TR in vitro when the...

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Autors principals: Giera, Stefanie, Bansal, Ruby, Ortiz-Toro, Theresa M., Taub, Daniel G., Zoeller, R. Thomas
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115602/
https://ncbi.nlm.nih.gov/pubmed/21540284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1490
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