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Formal Synthesis of Leustroducsin B via Reformatsky/Claisen Condensation of Silyl Glyoxylates

[Image: see text] A formal synthesis of leustroducsin B has been completed. The synthesis relies upon a recently developed Reformatsky/Claisen condensation of silyl glyoxylates and enantioenriched β-lactones that establishes two of the molecule’s three core stereocenters and permits further elaborat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Greszler, Stephen N., Malinowski, Justin T., Johnson, Jeffrey S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115596/
https://ncbi.nlm.nih.gov/pubmed/21591684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2011192
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