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Biological Functions of the Low and High Molecular Weight Protein Isoforms of Fibroblast Growth Factor-2 in Cardiovascular Development and Disease

Fibroblast growth factor 2 (FGF2) consists of multiple protein isoforms (low molecular weight, LMW, and high molecular weight, HMW) produced by alternative translation from the Fgf2 gene. These protein isoforms are localized to different cellular compartments, indicating unique biological activity....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liao, Siyun, Bodmer, Janet, Pietras, Daniel, Azhar, Mohamad, Doetschman, Tom, Schultz, Jo El J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115589/
https://ncbi.nlm.nih.gov/pubmed/18773489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21677
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