The Subthalamic Nucleus becomes a Generator of Bursts in the Dopamine-Depleted State. Its High Frequency Stimulation Dramatically Weakens Transmission to the Globus Pallidus

Excessive burst firing in the dopamine-depleted basal ganglia correlates with severe motor symptoms of Parkinson's disease that are attenuated by high frequency electrical stimulation of the subthalamic nucleus (STN). Here we test the hypothesis that pathological bursts in dopamine-deprived bas...

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Bibliografiska uppgifter
Huvudupphovsmän: Ammari, Rachida, Bioulac, Bernard, Garcia, Liliana, Hammond, Constance
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Research Foundation 2011
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115486/
https://ncbi.nlm.nih.gov/pubmed/21716635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2011.00043
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