Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist

Several recent studies suggest functional and molecular interactions between striatal adenosine A(2A) and cannabinoid CB(1) receptors. Here we demonstrate that A(2A) receptors selectively modulate reinforcing effects of cannabinoids. We studied effects of A(2A) receptor blockade on the reinforcing e...

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Hauptverfasser: Justinová, Zuzana, Ferré, Sergi, Redhi, Godfrey H., Mascia, Paola, Stroik, Jessica, Quarta, Davide, Yasar, Sevil, Müller, Christa E., Franco, Rafael, Goldberg, Steven R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115444/
https://ncbi.nlm.nih.gov/pubmed/21054689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2010.00258.x
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