Adaptive evolution of the vertebrate skeletal muscle sodium channel

Tetrodotoxin (TTX) is a highly potent neurotoxin that blocks the action potential by selectively binding to voltage-gated sodium channels (Na(v)). The skeletal muscle Na(v) (Na(v)1.4) channels in most pufferfish species and certain North American garter snakes are resistant to TTX, whereas in most m...

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Detalhes bibliográficos
Main Authors: Lu, Jian, Zheng, Jianzhou, Xu, Qinggang, Chen, Keping, Zhang, Chiyu
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115330/
https://ncbi.nlm.nih.gov/pubmed/21734837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572011000200026
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