Genetic and epigenetic X-chromosome variations in a parthenogenetic human embryonic stem cell line

PURPOSE: To assess the genetic and epigenetic status of parthenogenetic human embryonic stem cells (phESCs). METHODS: Cytogenetics, X chromosome inactivation (XCI) and gene expression patterns were analyzed in one phESC line (FY-phES-018) that was derived from our laboratory. RESULTS: FY-phES-018 ce...

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Detalhes bibliográficos
Main Authors: Liu, Weiqiang, Yin, Yifei, Jiang, Yonghua, Kou, Chaohui, Luo, Yumei, Huang, Shengchang, Zheng, Yuhong, Li, Shaoying, Li, Qing, Guo, Liyuan, Gao, Shaorong, Sun, Xiaofang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Stem Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114959/
https://ncbi.nlm.nih.gov/pubmed/21161365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-010-9517-1
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