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Moving Forward in Human Cancer Risk Assessment

BACKGROUND: The current safety paradigm for assessing carcinogenic properties of drugs, cosmetics, industrial chemicals, and environmental exposures relies mainly on in vitro genotoxicity testing followed by 2-year rodent bioassays. This testing battery is extremely sensitive but has low specificity...

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Bibliografiske detaljer
Main Authors: Paules, Richard S., Aubrecht, Jiri, Corvi, Raffaella, Garthoff, Bernward, Kleinjans, Jos C.
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114805/
https://ncbi.nlm.nih.gov/pubmed/21147607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002735
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