Allelic Variants of Melanocortin 3 Receptor Gene (MC3R) and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets

INTRODUCTION: The melanocortin system plays an important role in energy homeostasis. Mice genetically deficient in the melanocortin-3 receptor gene have a normal body weight with increased body fat, mild hypophagia compared to wild-type mice. In humans, Thr6Lys and Val81Ile variants of the melanocor...

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Detalhes bibliográficos
Main Authors: Santos, José L., De la Cruz, Rolando, Holst, Claus, Grau, Katrine, Naranjo, Carolina, Maiz, Alberto, Astrup, Arne, Saris, Wim H. M., MacDonald, Ian, Oppert, Jean-Michel, Hansen, Torben, Pedersen, Oluf, Sorensen, Thorkild I. A., Martinez, J. Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114803/
https://ncbi.nlm.nih.gov/pubmed/21695122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019934
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