Drosophila Melanogaster as a Model System for Studies of Islet Amyloid Polypeptide Aggregation

BACKGROUND: Recent research supports that aggregation of islet amyloid polypeptide (IAPP) leads to cell death and this makes islet amyloid a plausible cause for the reduction of beta cell mass, demonstrated in patients with type 2 diabetes. IAPP is produced by the beta cells as a prohormone, and pro...

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Hauptverfasser: Schultz, Sebastian Wolfgang, Nilsson, K. Peter R., Westermark, Gunilla Torstensdotter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114789/
https://ncbi.nlm.nih.gov/pubmed/21695120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020221
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