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Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients
BACKGROUND: High-dose Interferon (HDI) therapy produces a clinical response and achieves relapse-free survival in 20-33% of patients with operable high risk or metastatic melanoma. However, patients may develop significant side effects frequently necessitating dose reduction or discontinuation of th...
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Format: | Artigo |
Jezik: | Inglês |
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BioMed Central
2011
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114759/ https://ncbi.nlm.nih.gov/pubmed/21545749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-52 |
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