Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients

BACKGROUND: High-dose Interferon (HDI) therapy produces a clinical response and achieves relapse-free survival in 20-33% of patients with operable high risk or metastatic melanoma. However, patients may develop significant side effects frequently necessitating dose reduction or discontinuation of th...

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Detalhes bibliográficos
Main Authors: Simons, Diana L, Lee, Gerald, Kirkwood, John M, Lee, Peter P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114759/
https://ncbi.nlm.nih.gov/pubmed/21545749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-52
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