TLR1/2 Activation during Heterologous Prime-Boost Vaccination (DNA-MVA) Enhances CD8+ T Cell Responses Providing Protection against Leishmania (Viannia)

BACKGROUND: Leishmania (Viannia) parasites present particular challenges, as human and murine immune responses to infection are distinct from other Leishmania species, indicating a unique interaction with the host. Further, vaccination studies utilizing small animal models indicate that modalities a...

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Detalhes bibliográficos
Main Authors: Jayakumar, Asha, Castilho, Tiago M., Park, Esther, Goldsmith-Pestana, Karen, Blackwell, Jenefer M., McMahon-Pratt, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114751/
https://ncbi.nlm.nih.gov/pubmed/21695103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001204
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