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A Multicentre Randomized Controlled Trial of the Efficacy and Safety of Single-Dose Praziquantel at 40 mg/kg vs. 60 mg/kg for Treating Intestinal Schistosomiasis in the Philippines, Mauritania, Tanzania and Brazil

BACKGROUND: Praziquantel at 40 mg/kg in a single dose is the WHO recommended treatment for all forms of schistosomiasis, but 60 mg/kg is also deployed nationally. METHODOLOGY/PRINCIPAL FINDINGS: Four trial sites in the Philippines, Mauritania, Tanzania and Brazil enrolled 856 patients using a common...

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Detalhes bibliográficos
Main Authors: Olliaro, Piero L., Vaillant, Michel T., Belizario, Vincente J., Lwambo, Nicholas J. S., Ouldabdallahi, Mohamed, Pieri, Otavio S., Amarillo, Maria L., Kaatano, Godfrey M., Diaw, Mamadou, Domingues, AnaLucia C., Favre, Tereza C., Lapujade, Olivier, Alves, Fabiana, Chitsulo, Lester
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114749/
https://ncbi.nlm.nih.gov/pubmed/21695161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001165
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