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Meta-Alignment with Crumble and Prune: Partitioning very large alignment problems for performance and parallelization

BACKGROUND: Continuing research into the global multiple sequence alignment problem has resulted in more sophisticated and principled alignment methods. Unfortunately these new algorithms often require large amounts of time and memory to run, making it nearly impossible to run these algorithms on la...

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Detalhes bibliográficos
Main Authors: Roskin, Krishna M, Paten, Benedict, Haussler, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114744/
https://ncbi.nlm.nih.gov/pubmed/21569267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-144
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