Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching

Airway surface liquid (ASL) volume depletion and mucus accumulation occur in cystic fibrosis (CF). The ASL comprises a superficial mucus layer (ML) overlying a periciliary fluid layer (PCL) that contacts surface epithelial cells. We measured viscosity of the ML and PCL from the diffusion of FITC-dex...

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Bibliografiske detaljer
Main Authors: Derichs, Nico, Jin, Byung-Ju, Song, Yuanlin, Finkbeiner, Walter E., Verkman, A. S.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2011
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114535/
https://ncbi.nlm.nih.gov/pubmed/21427214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-179549
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