Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis

Emerging evidence suggests that the tumor suppressor p53 is also a crucial regulator for many physiological processes. Previous observations indicate that p53 suppresses inflammation by inhibiting inflammatory antigen-presenting cells. To investigate the potential role of p53 in autoimmune effector...

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Detalhes bibliográficos
Main Authors: Zhang, Shuzhong, Zheng, Mingquan, Kibe, Ryoko, Huang, Yunping, Marrero, Luis, Warren, Samantha, Zieske, Arthur W., Iwakuma, Tomoo, Kolls, Jay K., Cui, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114529/
https://ncbi.nlm.nih.gov/pubmed/21471252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-175299
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