Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor-β: A Model for Diabetic Podocytopathy

OBJECTIVE: Diabetic nephropathy is associated with dedifferentiation of podocytes, losing the specialized features required for efficient glomerular function and acquiring a number of profibrotic, proinflammatory, and proliferative features. These result from tight junction and cytoskeletal rearrang...

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Библиографические подробности
Главные авторы: Herman-Edelstein, Michal, Thomas, Merlin C., Thallas-Bonke, Vicki, Saleem, Moin, Cooper, Mark E., Kantharidis, Phillip
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2011
Предметы:
Complications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114395/
https://ncbi.nlm.nih.gov/pubmed/21521871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1110
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