Effect of Gastric Bypass Surgery on the Absorption and Bioavailability of Metformin

OBJECTIVE: Use of gastric bypass surgery is common and increasing. Over 40% of patients in diabetes remission after gastric bypass surgery may redevelop diabetes within 5 years. Metformin, the first-line drug for diabetes, has low bioavailability and slow, incomplete gastrointestinal absorption. We...

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Main Authors: Padwal, Raj S., Gabr, Raniah Q., Sharma, Arya M., Langkaas, Lee-Ann, Birch, Dan W., Karmali, Shahzeer, Brocks, Dion R.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2011
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114332/
https://ncbi.nlm.nih.gov/pubmed/21478461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-2140
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