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Presynaptic silencing is an endogenous neuroprotectant during excitotoxic insults

Glutamate release is a root cause of acute and delayed neuronal damage in response to hypoxic/ischemic insults. Nevertheless, therapeutics that target the postsynaptic compartment have been disappointing clinically. Here we explored whether presynaptic silencing (muting) of glutamatergic terminals i...

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Sonraí Bibleagrafaíochta
Main Authors: Hogins, Joshua, Crawford, Devon C., Jiang, Xiaoping, Mennerick, Steven
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114267/
https://ncbi.nlm.nih.gov/pubmed/21605675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.05.005
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