RIG-like Helicase Innate Immunity Inhibits Vascular Endothelial Growth Factor Tissue Responses via a Type I IFN–dependent Mechanism

Rationale: Vascular endothelial growth factor (VEGF) regulates vascular, inflammatory, remodeling, and cell death responses. It plays a critical role in normal pulmonary physiology, and VEGF excess and deficiency have been implicated in the pathogenesis of asthma and chronic obstructive pulmonary di...

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Hlavní autoři: Ma, Bing, Dela Cruz, Charles S., Hartl, Dominik, Kang, Min-Jong, Takyar, Shervin, Homer, Robert J., Lee, Chun Geun, Elias, Jack A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
Témata:
A. Chronic Obstructive Pulmonary Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114061/
https://ncbi.nlm.nih.gov/pubmed/21278304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201008-1276OC
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