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Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

BACKGROUND: Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. Approximately 95% of patients with Type 1 diabetes develop some degree of retinopathy within 25 years of diagnosis despite normalization of blood glucose by insulin therapy. The goal of this study was to ide...

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Autori principali: Bixler, Georgina V, VanGuilder, Heather D, Brucklacher, Robert M, Kimball, Scot R, Bronson, Sarah K, Freeman, Willard M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113923/
https://ncbi.nlm.nih.gov/pubmed/21575160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-4-40
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