GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

BACKGROUND: Growth-differentiation factor-15 (GDF-15) is a stress-responsive, transforming growth factor-β-related cytokine, which has recently been reported to be elevated in serum of patients with idiopathic pulmonary arterial hypertension (IPAH). The aim of the study was to examine the expression...

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Main Authors:	Nickel, Nils, Jonigk, Danny, Kempf, Tibor, Bockmeyer, Clemens L, Maegel, Lavinia, Rische, Johanna, Laenger, Florian, Lehmann, Ulrich, Sauer, Clemens, Greer, Mark, Welte, Tobias, Hoeper, Marius M, Golpon, Heiko A
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2011
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3113721/ https://ncbi.nlm.nih.gov/pubmed/21548946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-62
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GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

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