Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1

Muscle tissue is the major site for insulin-stimulated glucose uptake in vivo, due primarily to the recruitment of the insulin-sensitive glucose transporter (GLUT4) to the plasma membrane. Surprisingly, virtually all cultured muscle cells express little or no GLUT4. We show here that adenovirus-medi...

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Autors principals: Michael, Laura F., Wu, Zhidan, Cheatham, R. Bentley, Puigserver, Pere, Adelmant, Guillaume, Lehman, John J., Kelly, Daniel P., Spiegelman, Bruce M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC31136/
https://ncbi.nlm.nih.gov/pubmed/11274399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061035098
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