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Translational recoding as a feedback controller: systems approaches reveal polyamine-specific effects on the antizyme ribosomal frameshift

The antizyme protein, Oaz1, regulates synthesis of the polyamines putrescine, spermidine and spermine by controlling stability of the polyamine biosynthetic enzyme, ornithine decarboxylase. Antizyme mRNA translation depends upon a polyamine-stimulated +1 ribosomal frameshift, forming a complex negat...

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Bibliografiska uppgifter
Huvudupphovsmän: Rato, Claudia, Amirova, Svetlana R., Bates, Declan G., Stansfield, Ian, Wallace, Heather M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113565/
https://ncbi.nlm.nih.gov/pubmed/21303766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1349
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