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Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity
BACKGROUND: 3,4-Methylenedioxymethamphetamine (MDMA) produces a neuroinflammatory reaction in rat brain characterized by an increase in interleukin-1 beta (IL-1β) and microglial activation. The CB2 receptor agonist JWH-015 reduces both these changes and partially protects against MDMA-induced neurot...
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Główni autorzy: | , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
BioMed Central
2011
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113340/ https://ncbi.nlm.nih.gov/pubmed/21595923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-53 |
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