Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain

1. ABSTRACT: BACKGROUND: Cyclic phosphatidic acid (cPA) is a structural analog of lysophosphatidic acid (LPA), but possesses different biological functions, such as the inhibition of autotaxin (ATX), an LPA-synthesizing enzyme. As LPA is a signaling molecule involved in nociception in the peripheral...

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Detalhes bibliográficos
Main Authors: Kakiuchi, Yasutaka, Nagai, Jun, Gotoh, Mari, Hotta, Harumi, Murofushi, Hiromu, Ogawa, Tomoyo, Ueda, Hiroshi, Murakami-Murofushi, Kimiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113318/
https://ncbi.nlm.nih.gov/pubmed/21569544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-33
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