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Deficits in Memory Tasks of Mice with CREB Mutations Depend on Gene Dosage

Studies in Aplysia, Drosophila, and mice have shown that the transcription factor CREB is involved in formation and retention of long-term memory. To analyze the impact of differential CREB levels on learning and memory, we varied the gene dosage of CREB in two strains of mutant mice: (1) CREBαΔ mic...

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Autors principals: Gass, Peter, Wolfer, David P., Balschun, Detlef, Rudolph, Dorothea, Frey, Uwe, Lipp, Hans-Peter, Schütz, Günther
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC311267/
https://ncbi.nlm.nih.gov/pubmed/10454354
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