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Higher Seizure Susceptibility and Enhanced Tyrosine Phosphorylation of N-Methyl-d-Aspartate Receptor Subunit 2B in fyn Transgenic Mice

Earlier work has suggested that Fyn tyrosine kinase plays an important role in synaptic plasticity. To understand the downstream targets of Fyn signaling cascade in neurons, we generated transgenic mice expressing either a constitutively activated form of Fyn or native Fyn in neurons of the forebrai...

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Detalles Bibliográficos
Main Authors: Kojima, Nobuhiko, Ishibashi, Hidetoshi, Obata, Kunihiko, Kandel, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC311255/
https://ncbi.nlm.nih.gov/pubmed/10489260
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