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Enhanced Hippocampal CA1 LTP but Normal Spatial Learning in Inositol 1,4,5-trisphosphate 3-kinase(A)-Deficient Mice

To define the physiological role of IP(3)3-kinase(A) in vivo, we have generated a mouse strain with a null mutation of the IP(3)3-kinase(A) locus by gene targeting. Homozygous mutant mice were fully viable, fertile, apparently normal, and did not show any morphological anomaly in brain sections. In...

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Detalhes bibliográficos
Publicado no:Learn Mem
Principais autores: Jun, Kisun, Choi, Gildon, Yang, Sung-Gu, Choi, Kwan Yong, Kim, Hyun, Chan, Guy C.K., Storm, Daniel R., Albert, Claudia, Mayr, Georg W., Lee, Chang-Joong, Shin, Hee-Sup
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311247/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454357/
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