TGF-β signalling pathway and breast cancer susceptibility

BACKGROUND: TGF-β acts as a suppressor of primary tumour initiation but has been implicated as a promoter of the later malignant stages. Here associations with risk of invasive breast cancer are assessed for SNPs tagging seventeen genes in the canonical TGF-β ALK5/SMADs 2&3 and ALK1/SMADs 1&...

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Autors principals: Scollen, Serena, Luccarini, Craig, Baynes, Caroline, Driver, Kristy, Humphreys, Manjeet K., Garcia-Closas, Montserrat, Figueroa, Jonine, Lissowska, Jolanta, Pharoah, Paul D., Easton, Douglas F., Hesketh, Robin, Metcalfe, James C, Dunning, Alison M
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112459/
https://ncbi.nlm.nih.gov/pubmed/21527583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0062
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