Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection

BACKGROUND: The Plasmodium falciparum merozoite surface protein Pf38 is targeted by antibodies of malaria immune adults and has been shown to be under balancing (immune) selection in a Gambian parasite population, indicating potential as a malaria vaccine candidate. This study explores the populatio...

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Detalhes bibliográficos
Main Authors: Reeder, John C, Wapling, Johanna, Mueller, Ivo, Siba, Peter M, Barry, Alyssa E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112457/
https://ncbi.nlm.nih.gov/pubmed/21569602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-126
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