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The Ras-ERK and PI3K-mTOR Pathways: Cross-talk and Compensation

The Ras-ERK (extracellular signal-regulated kinase) and PI3K (phosphatidylinositol 3-kinase)-mTOR (mammalian target of rapamycin) signaling pathways are the cell’s chief mechanisms for controlling cell survival, differentiation, proliferation, metabolism, and motility in response to extracellular cu...

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Detalhes bibliográficos
Main Authors: Mendoza, Michelle C., Er, E. Emrah, Blenis, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112285/
https://ncbi.nlm.nih.gov/pubmed/21531565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.03.006
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