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Impact of site-specific N-glycosylation on cellular secretion, activity and specific activity of the plasma phospholipid transfer protein

The plasma phospholipid transfer protein (PLTP) plays a key role in lipid and lipoprotein metabolism. It has six potential N-glycosylation sites. To study the impact of these sites on PLTP secretion and activity, six variants containing serine to alanine point mutations were prepared by site-directe...

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Detalhes bibliográficos
Main Authors: Albers, John J., Day, Joseph R., Wolfbauer, Gertrud, Kennedy, Hal, Vuletic, Simona, Cheung, Marian C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112057/
https://ncbi.nlm.nih.gov/pubmed/21515415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2011.04.004
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