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Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

In a recent genome-wide association study, variants in 8 genes were associated with VWF level, a risk factor for venous thrombosis (VT). In an independent, population-based, case-control study of incident VT, we tested hypotheses that variants in these genes would be associated with risk. Cases were...

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Autors principals: Smith, Nicholas L., Rice, Kenneth M., Bovill, Edwin G., Cushman, Mary, Bis, Joshua C., McKnight, Barbara, Lumley, Thomas, Glazer, Nicole L., van Hylckama Vlieg, Astrid, Tang, Weihong, Dehghan, Abbas, Strachan, David P., O'Donnell, Christopher J., Rotter, Jerome I., Heckbert, Susan R., Psaty, Bruce M., Rosendaal, Frits R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112044/
https://ncbi.nlm.nih.gov/pubmed/21163921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-315473
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