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A more efficient and specific strategy in the ablation of mRNA in Xenopus laevis using mixtures of antisense oligos.
Previously, antisense oligodeoxyribonucleotides (oligos) have been used to ablate specific mRNAs from the maternal RNA pool of Xenopus laevis oocytes. However, this strategy is limited by the dose of oligo which can be used and the fact that 100% cleavage of the target RNA is rare. Further, non-spec...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1993
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC311199/ https://ncbi.nlm.nih.gov/pubmed/8233799 |
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