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Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

Androgens regulate body composition in youth and declining testosterone that occurs with aging is associated with muscle wasting, increased fat mass and osteopenia. Transgenic mice with targeted androgen receptor (AR) overexpression in mesenchymal stem cells (MSC) were generated to explore the role...

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Autori principali: Semirale, Anthony A., Zhang, Xiaowei, Wiren, Kristine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111903/
https://ncbi.nlm.nih.gov/pubmed/21381083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23098
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