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Comparative analysis of the regulation of the interferon-inducible protein kinase PKR by Epstein-Barr virus RNAs EBER-1 and EBER-2 and adenovirus VAI RNA.

The interferon-inducible protein kinase PKR interacts with a number of small viral RNA species, including adenovirus VAI RNA and the Epstein-Barr virus-encoded RNA EBER-1. These RNAs bind to PKR and protect protein synthesis from inhibition by double-stranded RNA in the reticulocyte lysate system. U...

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Detalhes bibliográficos
Main Authors: Sharp, T V, Schwemmle, M, Jeffrey, I, Laing, K, Mellor, H, Proud, C G, Hilse, K, Clemens, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC311179/
https://ncbi.nlm.nih.gov/pubmed/7901835
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