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EGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix
The epidermal growth factor receptor (EGFR) and its ligands regulate key processes of cell biology, such as proliferation, survival, differentiation, migration, and tumorigenesis. We previously showed that EGFR signaling pathway is an important bone regulator and it primarily plays an anabolic role...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111753/ https://ncbi.nlm.nih.gov/pubmed/21381079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23094 |
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