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Determinants of CpG Islands: Expression in Early Embryo and Isochore Structure

In an attempt to understand the origin of CpG islands (CGIs) in mammalian genomes, we have studied their location and structure according to the expression pattern of genes and to the G + C content of isochores in which they are embedded. We show that CGIs located over the transcription start site (...

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Detalles Bibliográficos
Main Authors: Ponger, Loïc, Duret, Laurent, Mouchiroud, Dominique
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC311164/
https://ncbi.nlm.nih.gov/pubmed/11691850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174501
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