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SNP Genotyping by Multiplexed Solid-Phase Amplification and Fluorescent Minisequencing

The emerging role of single-nucleotide polymorphisms (SNPs) in clinical association and pharmacogenetic studies has created a need for high-throughput genotyping technologies. We describe a novel method for multiplexed genotyping of SNPs that employs PCR amplification on microspheres. Oligonucleotid...

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Autori principali: Shapero, Michael H., Leuther, Kerstin K., Nguyen, Anhthu, Scott, Melissa, Jones, Keith W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC311152/
https://ncbi.nlm.nih.gov/pubmed/11691857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.205001
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