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Formation of a GNRA tetraloop in P5abc can disrupt an interdomain interaction in the Tetrahymena group I ribozyme

The secondary structure of a truncated P5abc subdomain (tP5abc, a 56-nucleotide RNA) of the Tetrahymena thermophila group I intron ribozyme changes when its tertiary structure forms. We have now used heteronuclear NMR spectroscopy to determine its conformation in solution. The tP5abc RNA that contai...

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Hlavní autoři: Zheng, Minxue, Wu, Ming, Tinoco, Ignacio
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC31114/
https://ncbi.nlm.nih.gov/pubmed/11274387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051608598
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