Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens

BACKGROUND: This study compared the central nervous system (CNS) metastasis incidence between a temozolomide- and a dacarbazine-based regimen in untreated stage IV melanoma patients. METHODS: A total of 150 patients were randomly assigned to receive either oral temozolomide (200 mg m(−2) per day; da...

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Detalhes bibliográficos
Main Authors: Chiarion-Sileni, V, Guida, M, Ridolfi, L, Romanini, A, Del Bianco, P, Pigozzo, J, Brugnara, S, Colucci, G, Ridolfi, R, De Salvo, G L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111207/
https://ncbi.nlm.nih.gov/pubmed/21610711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.178
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