Continuous low-dose cyclophosphamide and methotrexate combined with celecoxib for patients with advanced cancer

BACKGROUND: Combined therapy of metronomic cyclophosphamide, methotrexate and high-dose celecoxib targeting angiogenesis was used in a phase II trial. METHODS: Patients with advanced cancer received oral cyclophosphamide 50 mg o.d., celecoxib 400 mg b.d. and methotrexate 2.5 mg b.d. for two consecut...

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Detalhes bibliográficos
Main Authors: Khan, O A, Blann, A D, Payne, M J, Middleton, M R, Protheroe, A S, Talbot, D C, Taylor, M, Han, C, Patil, M, Harris, A L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111194/
https://ncbi.nlm.nih.gov/pubmed/21587257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.154
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