Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer

BACKGROUND: MicroRNAs are tiny non-coding small endogenous RNAs that regulate gene expression by translational repression, mRNA cleavage and mRNA inhibition. The aim of this study was to investigate the hypermethylation of miR-34b/c and miR-148a in colorectal cancer, and correlate this data to clini...

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Bibliografische gegevens
Hoofdauteurs: Kalimutho, M, Di Cecilia, S, Del Vecchio Blanco, G, Roviello, F, Sileri, P, Cretella, M, Formosa, A, Corso, G, Marrelli, D, Pallone, F, Federici, G, Bernardini, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
Onderwerpen:
Molecular Diagnostics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111174/
https://ncbi.nlm.nih.gov/pubmed/21610744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.82
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