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Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products

A detailed bioinformatics analysis of six glycopeptide biosynthetic gene clusters isolated from soil environmental DNA (eDNA) mega-libraries indicates that a subset of these gene clusters contains collections of tailoring enzymes that are predicted to result in the production of new glycopeptide con...

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Detalhes bibliográficos
Main Authors: Banik, Jacob J., Craig, Jeffrey W., Calle, Paula Y., Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111151/
https://ncbi.nlm.nih.gov/pubmed/20945895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105825a
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